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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Sctr
secretin receptor
MGI:2441720
30 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Sctrtm1Bkcc/Sctrtm1Bkcc
B6.129S7-Sctrtm1Bkcc
abnormal circulating antidiuretic hormone level J:166370
abnormal cytokine secretion J:121376
abnormal drinking behavior J:166370
abnormal kidney cortex morphology J:121376
abnormal kidney medulla morphology J:121376
abnormal response/metabolism to endogenous compounds J:166370
decreased urine creatinine level J:121376
decreased urine osmolality J:121376
decreased urine potassium level J:121376
decreased urine sodium level J:121376
decreased urine urea nitrogen level J:121376
dilated kidney collecting duct J:121376
expanded mesangial matrix J:121376
glomerulosclerosis J:121376
increased circulating glucose level J:121376
increased glomerular capsule space J:121376
increased macrophage cell number J:121376
kidney inflammation J:121376
polydipsia J:121376
polyuria J:121376
Sctrtm1Brd/Sctrtm1Brd
involves: 129S7/SvEvBrd * C57BL/6J
abnormal CNS synaptic transmission J:114853
abnormal dendritic spine morphology J:114853
abnormal excitatory postsynaptic potential J:114853
abnormal hippocampal pyramidal neuron dendrite morphology J:114853
abnormal social recognition J:114853
abnormal social/conspecific interaction J:114853
hyperactivity J:114853
impaired coordination J:114853
impaired spatial learning J:114853
reduced long term potentiation J:114853

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory