Tbx22 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbx22
T-box 22
MGI:2389465

17 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbx22^{tm1.1(KOMP)Vlcg}/Y C57BL/6N-Tbx22^{tm1.1(KOMP)Vlcg}/J	increased circulating HDL cholesterol level	J:211773
Tbx22^{tm1.1(KOMP)Vlcg}/Tbx22^{tm1.1(KOMP)Vlcg} C57BL/6N-Tbx22^{tm1.1(KOMP)Vlcg}/J	increased mean corpuscular hemoglobin	J:211773
Tbx22^tm1.1Sta/Y involves: 129/Sv * CD-1	abnormal bone mineralization	J:153100
	abnormal intramembranous bone ossification	J:153100
	abnormal osteoblast differentiation	J:153100
	abnormal palatal rugae morphology	J:153100
	abnormal vomer bone morphology	J:153100
	choanal atresia	J:153100
	cleft secondary palate	J:153100
	decreased palatine bone horizontal plate size	J:153100
	palate bone hypoplasia	J:153100
	perinatal lethality, incomplete penetrance	J:153100
	persistent oronasal membrane	J:153100
	respiratory distress	J:153100
	tongue ankylosis	J:153100
Tbx22^tm1.1Sta/Tbx22^tm1.1Sta involves: 129 * CD-1	abnormal bone mineralization	J:153100
	abnormal intramembranous bone ossification	J:153100
	abnormal osteoblast differentiation	J:153100
	abnormal palatal rugae morphology	J:153100
	abnormal vomer bone morphology	J:153100
	choanal atresia	J:153100
	cleft secondary palate	J:153100
	decreased palatine bone horizontal plate size	J:153100
	palate bone hypoplasia	J:153100
	perinatal lethality, incomplete penetrance	J:153100
	persistent oronasal membrane	J:153100
	respiratory distress	J:153100
	small vomer bone	J:153100
	tongue ankylosis	J:153100
Tbx22^tm1Sta/Y Not Specified	no abnormal phenotype detected	J:153100
Tbx22^tm1Sta/Tbx22^tm1Sta Not Specified	no abnormal phenotype detected	J:153100

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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