About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tmc1
transmembrane channel-like gene family 1
MGI:2151016
27 phenotypes from 6 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Tmc1baringo/Tmc1baringo
involves: C57BL/6
abnormal organ of Corti supporting cell morphology J:181985
abnormal outer hair cell stereociliary bundle morphology J:181985
normal behavior/neurological phenotype J:181985
cochlear degeneration J:181985
cochlear inner hair cell degeneration J:181985
cochlear outer hair cell degeneration J:181985
impaired hearing J:181985
organ of Corti degeneration J:181985
Tmc1dn/Tmc1+
involves: STOCK Grhl3ct * M. m. molossinus
normal hearing/vestibular/ear phenotype J:22445
Tmc1dn/Tmc1+
STOCK Grhl3ct/J
normal hearing/vestibular/ear phenotype J:14069
Tmc1dn/Tmc1dn
involves: STOCK Grhl3ct * M. m. molossinus
abnormal ear morphology J:22445
abnormal hearing physiology J:22445
Tmc1dn/Tmc1dn
STOCK Grhl3ct/J
abnormal ear morphology J:236, J:1600, J:6409, J:28899, J:32691
abnormal hearing physiology J:236, J:1600, J:6409, J:6806, J:28899, J:32693
abnormal motor capabilities/coordination/movement J:236
abnormal otolith morphology J:236
abnormal scala media morphology J:236
abnormal stria vascularis morphology J:236
abnormal tectorial membrane morphology J:236
cochlear ganglion degeneration J:236
deafness J:236
Deiters cell degeneration J:236
head tossing J:236
normal nervous system phenotype J:6806
organ of Corti degeneration J:236
vestibular saccular macula degeneration J:236
Tmc1Mhdabth/Tmc1+
C3HeB/FeJ-Tmc1Mhdabth/Ieg
abnormal gait J:86685
deafness J:86685
Tmc1nice/Tmc1nice
involves: C57BL/6
abnormal Deiters cell morphology J:181985
abnormal outer hair cell stereociliary bundle morphology J:181985
normal behavior/neurological phenotype J:181985
cochlear degeneration J:181985
cochlear inner hair cell degeneration J:181985
cochlear outer hair cell degeneration J:181985
impaired hearing J:181985
Tmc1stitch/Tmc1stitch
involves: BALB/c * C57BL/6
normal hearing/vestibular/ear phenotype J:181985
impaired hearing J:181985
Tmc1stitch/Tmc1stitch
involves: C57BL/6
abnormal outer hair cell stereociliary bundle morphology J:181985
normal behavior/neurological phenotype J:181985
cochlear degeneration J:181985
cochlear inner hair cell degeneration J:181985
cochlear outer hair cell degeneration J:181985
impaired hearing J:181985
organ of Corti degeneration J:181985
Tmc1tm1.1Ajg/Tmc1tm1.1Ajg
B6.129-Tmc1tm1.1Ajg
abnormal hair cell mechanoelectric transduction J:184419
normal behavior/neurological phenotype J:184419
cochlear hair cell degeneration J:184419
cochlear inner hair cell degeneration J:184419
cochlear outer hair cell degeneration J:184419
deafness J:184419
increased or absent threshold for auditory brainstem response J:184419

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/12/2019
MGI 6.14
The Jackson Laboratory