Mpig6b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mpig6b
megakaryocyte and platelet inhibitory receptor G6b
MGI:2146995

22 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mpig6b^{tm1.1(KOMP)Vlcg}/Mpig6b^{tm1.1(KOMP)Vlcg} C57BL/6N-Mpig6b^{tm1.1(KOMP)Vlcg}/MbpMmucd	decreased bronchoconstrictive response	J:211773
	increased pulmonary respiratory rate	J:211773
Mpig6b^{tm1.1(KOMP)Vlcg}/Mpig6b^{tm1.1(KOMP)Vlcg} C57BL/6N-Mpig6b^{tm1.1(KOMP)Vlcg}/Ucd	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	decreased circulating phosphate level	J:211773
	enlarged spleen	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased mean platelet volume	J:211773
	increased spleen weight	J:211773
	small testis	J:211773
	thrombocytopenia	J:211773
Mpig6b^tm1.1Arte/Mpig6b^tm1.1Arte involves: C57BL/6NTac	abnormal bone marrow morphology	J:201266
	abnormal megakaryocyte differentiation	J:201266
	abnormal platelet physiology	J:201266
	abnormal spleen red pulp morphology	J:201266
	decreased platelet aggregation	J:201266
	decreased platelet ATP level	J:201266
	enlarged spleen	J:201266
	extramedullary hematopoiesis	J:201266
	increased bleeding time	J:201266
	increased mean platelet volume	J:201266
	increased megakaryocyte cell number	J:201266
	myelofibrosis	J:201266
	spleen fibrosis	J:201266
	thrombocytopenia	J:201266

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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