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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Sec24b
SEC24 homolog B, COPII coat complex component
MGI:2139764
29 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Sec24bem1(IMPC)Tcp/Sec24b+
C57BL/6NCrl-Sec24bem1(IMPC)Tcp/Tcp
abnormal eye morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Sec24bem1(IMPC)Tcp/Sec24bem1(IMPC)Tcp
C57BL/6NCrl-Sec24bem1(IMPC)Tcp/Tcp
abnormal embryo size J:211773
abnormal head shape J:211773
abnormal tail morphology J:211773
exencephaly J:211773
preweaning lethality, complete penetrance J:211773
Sec24bkrb/Sec24bkrb
involves: C57BL/6
craniorachischisis J:158452
Sec24bkrb/Sec24bkrb
involves: C57BL/6 * FVB/N
abnormal cardiac outflow tract development J:158680
abnormal cochlea morphology J:158680
abnormal cochlear inner hair cell morphology J:158680
abnormal cochlear outer hair cell morphology J:158680
abnormal lung lobe morphology J:173681
abnormal neural tube closure J:158680
abnormal organ of Corti morphology J:158680
abnormal orientation of outer hair cell stereociliary bundles J:158680
abnormal visceral yolk sac morphology J:158680
craniorachischisis J:158680, J:173681
herniated abdominal wall J:158680
lethality throughout fetal growth and development, complete penetrance J:158680
retroesophageal right subclavian artery J:158680
small lung J:173681
transposition of great arteries J:158680
ventricular hypoplasia J:158680
Sec24bm11Bei/Sec24bm11Bei
involves: A/J * C57BL/6
abnormal neural tube morphology J:199782
Sec24bY613X/Sec24bY613X
involves: C3H/He * C57BL/6
abnormal embryo size J:158452
abnormal orientation of inner hair cell stereociliary bundles J:158452
abnormal orientation of outer hair cell stereociliary bundles J:158452
craniorachischisis J:158452
failure of eyelid fusion J:158452
lethality throughout fetal growth and development, complete penetrance J:158452
omphalocele J:158452
open neural tube J:158452

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory