Ppm1l Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppm1l
protein phosphatase 1 (formerly 2C)-like
MGI:2139740

21 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppm1l^tm1Dgen/Ppm1l^tm1Dgen involves: 129P2/OlaHsd * C57BL/6J	decreased circulating free fatty acids level	J:134171
	improved glucose tolerance	J:134171
	increased body weight	J:134171
	increased circulating glucose level	J:134171
	increased systemic arterial blood pressure	J:134171
	increased total body fat amount	J:134171
Ppm1l^tm1Tkoba/Ppm1l^tm1Tkoba B6.Cg-Ppm1l^tm1Tkoba	postnatal lethality, complete penetrance	J:238086
Ppm1l^tm1Tkoba/Ppm1l^tm1Tkoba CBA.Cg-Ppm1l^tm1Tkoba	abnormal anterior commissure morphology	J:238086
	abnormal dorsal striatum morphology	J:238086
	abnormal forebrain morphology	J:238086
	decreased anterior commissure size	J:238086
	decreased corpus callosum size	J:238086
	decreased myelin sheath thickness	J:238086
	decreased striatum size	J:238086
	decreased survivor rate	J:238086
	dysmyelination	J:238086
	enlarged lateral ventricles	J:238086
	impaired coordination	J:238086
	impaired limb coordination	J:238086
	limb grasping	J:238086
	postnatal lethality, incomplete penetrance	J:238086

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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