Sgpp1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sgpp1
sphingosine-1-phosphate phosphatase 1
MGI:2135760

14 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Sgpp1^{tm1(KOMP)Vlcg}/Sgpp1^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal ceramide level	J:199597
	abnormal epidermal layer morphology	J:199597
	abnormal epidermis stratum corneum morphology	J:199597
	abnormal keratinocyte differentiation	J:199597
	abnormal skin appearance	J:199597, J:235035
	abnormal skin physiology	J:199597
	decreased body size	J:199597
	impaired skin barrier function	J:199597
	increased keratinocyte proliferation	J:199597
	postnatal lethality, incomplete penetrance	J:199597
	thick epidermis	J:199597
	thick epidermis stratum basale	J:199597
	thick epidermis stratum granulosum	J:199597
	thick epidermis stratum spinosum	J:199597

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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