Nucks1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
MGI:1934811

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nucks1^tm1.2Vter/Nucks1^tm1.2Vter involves: 129S2/SvPas * C57BL/6 * C57BL/6NSlc * FVB/N * SJL	decreased basal metabolism	J:211777
	decreased circulating adiponectin level	J:211777
	decreased energy expenditure	J:211777
	decreased locomotor activity	J:211777
	normal embryo phenotype	J:211777
	hepatic steatosis	J:211777
	normal homeostasis/metabolism phenotype	J:211777
	impaired glucose tolerance	J:211777
	increased body weight	J:211777
	increased circulating glucose level	J:211777
	increased circulating insulin level	J:211777
	increased circulating leptin level	J:211777
	increased food intake	J:211777
	increased pulmonary respiratory rate	J:211777
	increased renal fat pad weight	J:211777
	increased total body fat amount	J:211777
	insulin resistance	J:211777
Nucks1^{tm1b(EUCOMM)Hmgu}/Nucks1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Nucks1^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal kidney morphology	J:211773
	decreased circulating cholesterol level	J:211773
	decreased circulating HDL cholesterol level	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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