Litaf Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Litaf
LPS-induced TN factor
MGI:1929512

13 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Litaf^tm1.1Cwc/Litaf⁺ B6.Cg-Litaf^tm1.1Cwc	abnormal exocytosis	J:314784
	abnormal lysosome physiology	J:314784
	abnormal vacuole morphology	J:314784
	cellular phenotype	J:314784
	limb paralysis	J:314784
Litaf^tm1.1Cwc/Litaf^tm1.1Cwc B6.Cg-Litaf^tm1.1Cwc	abnormal exocytosis	J:314784
	abnormal lysosome physiology	J:314784
	abnormal vacuole morphology	J:314784
	normal cellular phenotype	J:314784
	limb paralysis	J:314784
Litaf^tm1.1Ics/Litaf^tm1.1Ics Not Specified	demyelination	J:186411
	impaired macrophage chemotaxis	J:186411
	increased macrophage cell number	J:186411
	increased susceptibility to injury	J:186411
	normal nervous system phenotype	J:186411
Litaf^tm1.2Cwc/Litaf^tm1.2Cwc C57BL/6-Litaf^tm1.2Cwc	abnormal exocytosis	J:314784
	abnormal lysosome physiology	J:314784
	abnormal vacuole morphology	J:314784
Litaf^tm1Samr/Litaf^tm1Samr involves: 129S4/SvJae	abnormal cytokine secretion	J:113750
Litaf^tm1Samr/Litaf^tm1Samr involves: 129S4/SvJae	decreased susceptibility to endotoxin shock	J:113750

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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