Arpc3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arpc3
actin related protein 2/3 complex, subunit 3
MGI:1928375

23 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arpc3^Gt(XG476)Byg/Arpc3^Gt(XG476)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal fibroblast chemotaxis	J:185040
	abnormal fibroblast physiology	J:185040
	embryonic lethality before implantation, complete penetrance	J:185040
	impaired fibroblast cell migration	J:185040
	impaired wound healing	J:185040
Arpc3^{tm1a(EUCOMM)Wtsi}/Arpc3^{tm1a(EUCOMM)Wtsi} C57BL/6N-Arpc3^{tm1a(EUCOMM)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Arpc3^tm1Ssod/Arpc3^tm1Ssod involves: 129S6/SvEvTac * C57BL/6NCrl	abnormal dendritic spine morphology	J:196577
	abnormal hippocampus pyramidal cell morphology	J:196577
Arpc3^tm1Ssod/Arpc3^tm1Ssod Tg(Camk2a-cre)T29-1Stl/0 involves: 129S6/SvEvTac * BALB/c * C57BL	abnormal dendritic spine morphology	J:196577
	abnormal object recognition memory	J:196577
	abnormal social/conspecific interaction behavior	J:196577
	abnormal spatial working memory	J:196577
	abnormal synapse morphology	J:196577
	normal behavior/neurological phenotype	J:196577
	decreased prepulse inhibition	J:196577
	hyperactivity	J:196577
	impaired long-term object recognition memory	J:196577
	impaired short-term object recognition memory	J:196577
	increased stereotypic behavior	J:196577
	increased vertical activity	J:196577
Arpc3^{Tn(sb-lacZ,GFP)T5.117Jtak}/Arpc3^tm1Jtak involves: 129S4/SvJae * C57BL/6	abnormal blastocyst morphology	J:111402
	embryonic lethality before implantation, complete penetrance	J:111402
Arpc3^{Tn(sb-lacZ,GFP)T5.117Jtak}/Arpc3^{Tn(sb-lacZ,GFP)T5.117Jtak} involves: C3H * C57BL * C57BL/6 * DBA	decreased body size	J:104039
Arpc3^{Tn(sb-lacZ,GFP)T5.117Jtak}/Arpc3^{Tn(sb-lacZ,GFP)T5.117Jtak} Not Specified	abnormal blastocyst morphology	J:111402
	abnormal cell morphology	J:111402
	abnormal inner cell mass morphology	J:111402
	embryonic lethality before implantation, complete penetrance	J:111402

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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