Git1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Git1
GIT ArfGAP 1
MGI:1927140

30 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Git1^{Gt(FHCRC-GT-S10-12C1)Sor}/Git1⁺ involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:126878
Git1^{Gt(FHCRC-GT-S10-12C1)Sor}/Git1^{Gt(FHCRC-GT-S10-12C1)Sor} involves: 129S4/SvJaeSor * C57BL/6	abnormal brain wave pattern	J:171608
	abnormal CNS synaptic transmission	J:171608
	abnormal object recognition memory	J:171608
	abnormal spatial learning	J:171608
	decreased body weight	J:171608
	decreased miniature inhibitory postsynaptic current frequency	J:171608
	decreased neuron number	J:171608
	hyperactivity	J:171608
	impaired swimming	J:171608
	postnatal lethality, incomplete penetrance	J:171608
Git1^tm1.2Rtp/Git1^tm1.2Rtp Not Specified	decreased anxiety-related response	J:150460
	decreased body weight	J:150460
	decreased fear-related response	J:150460
	decreased survivor rate	J:150460
	impaired contextual conditioning behavior	J:150460
	impaired cued conditioning behavior	J:150460
Git1^tm1Bcb/Git1^tm1Bcb involves: 129 * C57BL/6	abnormal dendrite morphology	J:158848
	abnormal lung development	J:158935
	abnormal lung vasculature morphology	J:158935
	abnormal operant conditioning behavior	J:158848
	normal cardiovascular system phenotype	J:158848
	cyanosis	J:158935
	decreased dendritic spine density	J:158848
	decreased survivor rate	J:158935
	decreased vascular endothelial cell number	J:158935
	decreased vascular endothelial cell proliferation	J:158935
	dilated respiratory conducting tube	J:158935
	lung hemorrhage	J:158935
	neonatal lethality, incomplete penetrance	J:158935
	normal nervous system phenotype	J:158848
	postnatal lethality, incomplete penetrance	J:158935
	respiratory distress	J:158935

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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