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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rassf5
Ras association (RalGDS/AF-6) domain family member 5
MGI:1926375
30 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Rassf5tm1Kina/Rassf5+
involves: C57BL/6 * CBA * ICR
lymphoid hypoplasia J:92670
Rassf5tm1Kina/Rassf5tm1Kina
B6.Cg-Rassf5tm1Kina
abnormal lymphocyte physiology J:168749
enlarged lymph nodes J:168749
enlarged spleen J:168749
glomerulonephritis J:168749
increased anti-double stranded DNA antibody level J:168749
increased B cell derived lymphoma incidence J:168749
increased B cell number J:168749
increased B cell proliferation J:168749
increased hepatocellular carcinoma incidence J:168749
increased IgG level J:168749
increased lung adenocarcinoma incidence J:168749
increased memory T cell number J:168749
increased plasma cell number J:168749
increased T cell number J:168749
increased T cell proliferation J:168749
increased urine protein level J:168749
Rassf5tm1Kina/Rassf5tm1Kina
involves: C57BL/6 * CBA * ICR
abnormal B cell differentiation J:92670
abnormal dendritic cell physiology J:92670
abnormal leukocyte migration J:92670
abnormal lymph node cell ratio J:92670
abnormal lymph node cortex morphology J:92670
abnormal spleen red pulp morphology J:92670
abnormal thymus cell ratio J:92670
abnormal thymus corticomedullary boundary morphology J:92670
abnormal thymus medulla morphology J:92670
decreased thymocyte number J:92670
spleen hypoplasia J:92670
Rassf5tm1Sblee/Rassf5tm1Sblee
involves: 129S6/SvEvTac * C57BL/6J
decreased fibroblast apoptosis J:166871
decreased sensitivity to xenobiotic induced morbidity/mortality J:166871

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory