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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hectd3
HECT domain E3 ubiquitin protein ligase 3
MGI:1923858
22 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Hectd3tm1(NCOM)Cmhd/Hectd3tm1(NCOM)Cmhd
C57BL/6N-Hectd3tm1(NCOM)Cmhd/Nju
abnormal bone structure J:211773
decreased body length J:211773
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased brain size J:211773
decreased grip strength J:211773
decreased lean body mass J:211773
decreased startle reflex J:211773
female infertility J:211773
male infertility J:211773
small heart J:211773
small liver J:211773
small lung J:211773
small spleen J:211773
small stomach J:211773
small thymus J:211773
Hectd3tm1Lex/Hectd3tm1Lex
FVB.129S5(B6)-Hectd3tm1Lex
decreased circulating interferon-beta level J:266602
decreased circulating interleukin-1 beta level J:266602
decreased circulating interleukin-6 level J:266602
decreased circulating tumor necrosis factor level J:266602
decreased susceptibility to bacterial infection J:266602
decreased susceptibility to bacterial infection induced morbidity/mortality J:266602

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory