Dnaaf2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnaaf2
dynein, axonemal assembly factor 2
MGI:1923566

40 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnaaf2^{tm1.1(KOMP)Vlcg}/Dnaaf2⁺ C57BL/6N-Dnaaf2^{tm1.1(KOMP)Vlcg}/J	abnormal sleep behavior	J:211773
	increased startle reflex	J:211773
Dnaaf2^{tm1.1(KOMP)Vlcg}/Dnaaf2^{tm1.1(KOMP)Vlcg} B6N(Cg)-Dnaaf2^{tm1.1(KOMP)Vlcg}/J	abnormal direction of heart looping	J:278736
	abnormal embryo development	J:279207
	abnormal left-right axis patterning	J:278736, J:279207
	abnormal neural tube closure	J:278736
	abnormal primitive node morphology	J:278736
	abnormal tail bud morphology	J:278736
	absent vitelline blood vessels	J:278736
	caudal body truncation	J:278736
	decreased embryo size	J:279207
	decreased embryonic cilium number	J:278736
	embryonic growth arrest	J:278736, J:279207
	embryonic growth retardation	J:278736
	embryonic lethality during organogenesis, complete penetrance	J:278736
	embryonic lethality, complete penetrance	J:279207
	failure of initiation of embryo turning	J:278736
	increased embryonic tissue cell apoptosis	J:278736
	increased neural tube apoptosis	J:278736
	increased tail bud apoptosis	J:278736
	pericardial edema	J:278736
Dnaaf2^{tm1.1(KOMP)Vlcg}/Dnaaf2^{tm1.1(KOMP)Vlcg} C57BL/6N-Dnaaf2^{tm1.1(KOMP)Vlcg}/J	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Dnaaf2^tm1.1Mkis/Dnaaf2^tm1.1Mkis involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj	abdominal situs inversus	J:201474
	abnormal brain ependyma motile cilium location or orientation	J:201474
	abnormal brain ependyma motile cilium morphology	J:201474
	abnormal brain ependyma motile cilium physiology	J:201474
	abnormal tracheal ciliated epithelium morphology	J:201474
	decreased body size	J:201474
	dextrocardia	J:201474
	enlarged brain ventricles	J:201474
	enlarged lateral ventricles	J:201474
	heterotaxia	J:201474
	hydrocephaly	J:201474
	immotile respiratory cilia	J:201474
	postnatal growth retardation	J:201474
	postnatal lethality, incomplete penetrance	J:201474
	right-sided stomach	J:201474
	situs inversus totalis	J:201474
	thin cerebral cortex	J:201474

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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