Dpp3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dpp3
dipeptidylpeptidase 3
MGI:1922471

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dpp3^{tm1b(EUCOMM)Hmgu}/Dpp3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Dpp3^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal optic disk morphology	J:211773
Dpp3^{tm1d(EUCOMM)Hmgu}/Dpp3^{tm1d(EUCOMM)Hmgu} involves: BALB/c * C57BL/6 * C57BL/6J * C57BL/6N * SJL	abnormal interferon-gamma secretion	J:294242
	decreased apoptosis	J:294242
	decreased body length	J:294242
	decreased body weight	J:294242
	decreased bone ossification	J:294242
	decreased bone volume	J:294242
	decreased length of long bones	J:294242
	decreased osteoblast cell number	J:294242
	decreased trabecular bone thickness	J:294242
	increased bone marrow cell number	J:294242
	increased bone resorption	J:294242
	increased bone trabecular spacing	J:294242
	increased interleukin-1 beta secretion	J:294242
	increased interleukin-6 secretion	J:294242
	increased interleukin-10 secretion	J:294242
	increased osteoclast cell number	J:294242
	increased osteoid thickness	J:294242
	increased osteoid volume	J:294242
	increased tumor necrosis factor secretion	J:294242
	normal mortality/aging	J:294242
	normal reproductive system phenotype	J:294242

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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