Tbc1d21 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbc1d21
TBC1 domain family, member 21
MGI:1921536

15 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbc1d21^em1(IMPC)J/Tbc1d21^em1(IMPC)J C57BL/6NJ-Tbc1d21^em1(IMPC)J/Mmjax	male infertility	J:211773
Tbc1d21^em1Osb/Tbc1d21^em1Osb involves: 129S2/SvPas * C57BL/6NSlc	abnormal sperm midpiece morphology	J:302631
	abnormal sperm mitochondrial sheath morphology	J:302631
	abnormal spermatid morphology	J:302631
	male infertility	J:302631
Tbc1d21^tm1.1Yhln/Tbc1d21^tm1.1Yhln involves: C57BL/6	abnormal mitochondrial morphology	J:299845
	abnormal mitochondrial shape	J:299845
	abnormal outer dense fiber morphology	J:299845
	abnormal sperm axoneme morphology	J:299845
	abnormal sperm flagellum morphology	J:299845
	abnormal sperm midpiece morphology	J:299845
	abnormal sperm mitochondrial sheath morphology	J:299845
	abnormal sperm physiology	J:299845
	decreased mitochondrial number	J:299845
	decreased sperm progressive motility	J:299845
	male infertility	J:299845
	oligozoospermia	J:299845
	normal reproductive system phenotype	J:299845
	teratozoospermia	J:299845

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23