Top1mt Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Top1mt
DNA topoisomerase 1, mitochondrial
MGI:1920210

12 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Top1mt^tm1.1Hlzh/Top1mt^tm1.1Hlzh Not Specified	abnormal autophagy	J:189886
	abnormal blood homeostasis	J:189886
	abnormal cell physiology	J:189886
	abnormal cellular glucose uptake	J:189886
	abnormal cellular respiration	J:189886
	abnormal liver physiology	J:189886
	abnormal mitochondrial morphology	J:189886
	abnormal mitochondrial physiology	J:189886
	abnormal redox activity	J:189886
	decreased fibroblast proliferation	J:189886
	increased mitochondrial number	J:189886
	oxidative stress	J:189886

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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