Ptcd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptcd1
pentatricopeptide repeat domain 1
MGI:1919049

19 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Ptcd1^{tm1(KOMP)Vlcg}/Ptcd1⁺ C57BL/6N-Ptcd1^{tm1(KOMP)Vlcg}	abnormal hepatocyte mitochondrial morphology	J:256004
	abnormal mitochondrial crista morphology	J:256004
	abnormal mitochondrial physiology	J:256004
	abnormal oxidative phosphorylation	J:256004
	normal behavior/neurological phenotype	J:256004
	cardiac hypertrophy	J:256004
	decreased heart left ventricle size	J:256004
	hepatic steatosis	J:256004
	impaired glucose tolerance	J:256004
	increased cardiac muscle contractility	J:256004
	increased circulating leptin level	J:256004
	increased circulating triglyceride level	J:256004
	insulin resistance	J:256004
	liver fibrosis	J:256004
	obese	J:256004
	normal reproductive system phenotype	J:256004
	thick interventricular septum	J:256004
	thick ventricular wall	J:256004
Ptcd1^{tm1(KOMP)Vlcg}/Ptcd1^{tm1(KOMP)Vlcg} C57BL/6N-Ptcd1^{tm1(KOMP)Vlcg}	embryonic lethality, complete penetrance	J:256004

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23