Arhgap21 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arhgap21
Rho GTPase activating protein 21
MGI:1918685

19 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arhgap21^em1(IMPC)J/Arhgap21⁺ C57BL/6NJ-Arhgap21^em1(IMPC)J/Mmjax	abnormal auditory brainstem response	J:211773
	abnormal vocalization	J:211773
	decreased bone mineral content	J:211773
	decreased lean body mass	J:211773
	increased total body fat amount	J:211773
Arhgap21^em1(IMPC)J/Arhgap21^em1(IMPC)J C57BL/6NJ-Arhgap21^em1(IMPC)J/Mmjax	abnormal body wall morphology	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Arhgap21^{Gt(RRR629)Byg}/Arhgap21⁺ B6.129P2-Arhgap21^{Gt(RRR629)Byg}	abnormal hematopoietic stem cell physiology	J:262703
	decreased erythrocyte cell number	J:262703
	decreased erythroid progenitor cell number	J:262703
	decreased hematopoietic stem cell number	J:262703
	decreased hemoglobin content	J:262703
	increased leukocyte cell number	J:262703
	increased megakaryocyte cell number	J:262703
	increased megakaryocyte progenitor cell number	J:262703
	increased neutrophil cell number	J:262703
	increased susceptibility to injury	J:262703
	thrombocytopenia	J:262703
Arhgap21^{Gt(RRR629)Byg}/Arhgap21^{Gt(RRR629)Byg} B6.129P2-Arhgap21^{Gt(RRR629)Byg}	embryonic lethality between somite formation and embryo turning, complete penetrance	J:262703

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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