Esrp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Esrp1
epithelial splicing regulatory protein 1
MGI:1917326

37 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Esrp1^em1(IMPC)Mbp/Esrp1⁺ C57BL/6N-Esrp1^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	abnormal ovary morphology	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	edema	J:211773
	embryonic growth retardation	J:211773
	enlarged kidney	J:211773
	small kidney	J:211773
Esrp1^em1(IMPC)Mbp/Esrp1^em1(IMPC)Mbp C57BL/6N-Esrp1^em1(IMPC)Mbp/MbpMmucd	abnormal craniofacial morphology	J:211773
	abnormal limb morphology	J:211773
	cleft palate	J:211773
	edema	J:211773
	embryonic growth retardation	J:211773
	facial cleft	J:211773
	hemorrhage	J:211773
	polydactyly	J:211773
	preweaning lethality, complete penetrance	J:211773
Esrp1^m1Btlr/Esrp1^m1Btlr involves: C57BL/6J	circling	J:201716
	normal hearing/vestibular/ear phenotype	J:201716
	hyperactivity	J:201716
Esrp1^m1Btlr/Esrp1^tm1.2Rpc involves: 129S4/SvJae * C57BL/6 * C57BL/6J	cleft secondary palate	J:293624
Esrp1^tm1.1Rpc/Esrp1^tm1.1Rpc Tg(Tcfap2a-cre)1Will/0 involves: 129S4/SvJae * C57BL/6	abnormal palate morphology	J:293624
	bilateral cleft palate	J:293624
	bilateral cleft upper lip	J:293624
	cleft primary palate	J:293624
	cleft secondary palate	J:293624
	maxillary shelf hypoplasia	J:293624
	palatine bone hypoplasia	J:293624
	small premaxilla	J:293624
Esrp1^tm1.2Rpc/Esrp1^tm1.2Rpc involves: 129S4/SvJae * C57BL/6	abnormal lateral nasal prominence morphology	J:293624
	abnormal medial nasal prominence morphology	J:293624
	abnormal nasal pit morphology	J:293624
	abnormal palatal shelf fusion at midline	J:293624
	cleft palate	J:293624
	cleft upper lip	J:293624
	decreased palatal shelf size	J:293624
	maxillary shelf hypoplasia	J:293624
	palatal shelves fail to meet at midline	J:293624
Esrp1^tm1.2Rpc/Esrp1^tm1.2Rpc involves: 129S4/SvJae * C57BL/6 * C57BL/6J	bilateral cleft palate	J:226997
	bilateral cleft upper lip	J:226997
	cleft hard palate	J:226997
	cleft primary palate	J:226997
	cleft soft palate	J:226997
	normal limbs/digits/tail phenotype	J:226997
	neonatal lethality, complete penetrance	J:226997

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23