Emc10 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Emc10
ER membrane protein complex subunit 10
MGI:1916933

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Emc10^{Gt(OST181617)Lex}/Emc10^{Gt(OST181617)Lex} B6;129S5-Emc10^{Gt(OST181617)Lex}/Mmucd	improved glucose tolerance	J:171883
	increased anxiety-related response	J:171883
	reduced male fertility	J:171883
Emc10^tm1.2Smoc/Emc10^tm1.2Smoc involves: 129S6/SvEvTac * C57BL/6J * FVB/N * SJL/J	abnormal bicarbonate homeostasis	J:307574
	abnormal enzyme/coenzyme activity	J:307574
	abnormal sodium ion homeostasis	J:307574
	asthenozoospermia	J:307574
	decreased testis weight	J:307574
	hairpin sperm flagellum	J:307574
	impaired acrosome reaction	J:307574
	impaired fertilization	J:307574
	impaired sperm capacitation	J:307574
	kinked sperm flagellum	J:307574
	male infertility	J:307574
	oligozoospermia	J:307574
	reduced female fertility	J:307574
Emc10^{tm1b(EUCOMM)Wtsi}/Emc10^{tm1b(EUCOMM)Wtsi} C57BL/6N-Emc10^{tm1b(EUCOMM)Wtsi}/H	abnormal gait	J:211773
	abnormal locomotor behavior	J:211773
	abnormal vocalization	J:211773
	decreased fasting circulating glucose level	J:211773
	thin ventricular wall	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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