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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
MGI:1916882
8 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Arhgef12tm1.1Wet/Arhgef12tm1.1Wet
Tg(Lck-cre)548Jxm/0
involves: 129 * C57BL/6 * CBA
abnormal T cell proliferation J:149560
Arhgef12tm1b(KOMP)Wtsi/Arhgef12+
C57BL/6N-Arhgef12tm1b(KOMP)Wtsi/Tcp
abnormal sensory capabilities/reflexes/nociception J:211773
decreased circulating insulin level J:211773
Arhgef12tm1b(KOMP)Wtsi/Arhgef12tm1b(KOMP)Wtsi
C57BL/6N-Arhgef12tm1b(KOMP)Wtsi/Tcp
preweaning lethality, incomplete penetrance J:211773
Arhgef12tm1Sgkd/Arhgef12tm1Sgkd
involves: 129 * C57BL/6J
prenatal lethality, incomplete penetrance J:198274
Arhgef12tm1Soff/Arhgef12tm1Soff
Not Specified
normal cardiovascular system phenotype J:141641
decreased systemic arterial blood pressure J:141641
decreased vasoconstriction J:141641

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory