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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mocos
molybdenum cofactor sulfurase
MGI:1915841
57 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Mocosem2(IMPC)Ics/Mocos+
C57BL/6N-Mocosem2(IMPC)Ics/Ics
increased circulating cholesterol level J:211773
increased circulating HDL cholesterol level J:211773
increased total body fat amount J:211773
Mocosem2(IMPC)Ics/Mocos+
involves: C57BL/6N
decreased liver weight J:336718
normal growth/size/body region phenotype J:336718
Mocosem2(IMPC)Ics/Mocosem2(IMPC)Ics
involves: C57BL/6N
abnormal adipose tissue development J:336718
abnormal amino acid metabolism J:336718
abnormal glomerular capillary morphology J:336718
abnormal kidney collecting duct morphology J:336718
abnormal kidney morphology J:336718
abnormal kidney pelvis morphology J:336718
abnormal kidney pelvis smooth muscle morphology J:336718
abnormal kidney pelvis urothelium morphology J:336718
abnormal lipid metabolism J:336718
abnormal metabolism J:336718
abnormal redox activity J:336718
abnormal renal glomerulus morphology J:336718
abnormal renal tubule epithelium morphology J:336718
anemia J:336718
colorless urine J:336718
decreased blood uric acid level J:336718
decreased body size J:336718
decreased body weight J:336718
decreased circulating alanine transaminase level J:336718
decreased erythrocyte cell number J:336718
decreased hematocrit J:336718
decreased hemoglobin content J:336718
decreased kidney weight J:336718
decreased liver weight J:336718
decreased urine pH J:336718
dilated kidney collecting duct J:336718
dilated renal tubule J:336718
hydronephrosis J:336718
increased blood urea nitrogen level J:336718
increased brain weight J:336718
increased circulating alkaline phosphatase level J:336718
increased circulating creatinine level J:336718
increased circulating hypoxanthine level J:336718
increased circulating xanthine level J:336718
increased kidney cell proliferation J:336718
increased renal tubule apoptosis J:336718
increased urine hypoxanthine level J:336718
increased urine xanthine level J:336718
kidney failure J:336718
kidney inflammation J:336718
nephrolithiasis J:336718
pale kidney J:336718
perinatal lethality, incomplete penetrance J:336718
postnatal growth retardation J:336718
premature death J:336718
pup cannibalization J:336718
renal cast J:336718
renal interstitial fibrosis J:336718
renal tubular necrosis J:336718
renal tubule atrophy J:336718
small kidney J:336718
tubulointerstitial nephritis J:336718
ureter obstruction J:336718

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory