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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cthrc1
collagen triple helix repeat containing 1
MGI:1915838
36 phenotypes from 7 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cthrc1em1(IMPC)Mbp/Cthrc1em1(IMPC)Mbp
C57BL/6NCrl-Cthrc1em1(IMPC)Mbp/MbpMmucd 		abnormal kidney morphology J:211773
abnormal liver morphology J:211773
abnormal testis morphology J:211773
persistence of hyaloid vascular system J:211773
small kidney J:211773
small liver J:211773
small testis J:211773
Cthrc1tm1.1Suna/Cthrc1tm1.1Suna
Ctsktm1(cre)Ska/Ctsk+
involves: 129S6/SvEvTac * C57BL/6NCrlj * C57BL/6NTac * CBA/JNCrlj 		abnormal osteoid morphology J:201631
decreased bone mass J:201631
decreased bone ossification J:201631
decreased bone trabecula number J:201631
decreased trabecular bone thickness J:201631
increased bone trabecular spacing J:201631
osteoporosis J:201631
normal skeleton phenotype J:201631
Cthrc1tm1.1Suna/Cthrc1tm1.1Suna
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S6/SvEvTac * C57BL/6NTac * CD-1 		normal skeleton phenotype J:201631
Cthrc1tm1.2Suna/Cthrc1tm1.2Suna
involves: 129S6/SvEvTac * C57BL * C57BL/6NTac * DBA 		decreased bone mass J:201631
decreased bone trabecula number J:201631
decreased trabecular bone thickness J:201631
osteoporosis J:201631
Cthrc1tm1Haak/Cthrc1tm1Haak
B6.129S-Cthrc1tm1Haak 		abnormal bone ossification J:143940
abnormal osteoblast morphology J:143940
abnormal osteoblast physiology J:143940
decreased bone trabecula number J:143940
decreased osteoblast cell number J:143940
decreased osteoblast proliferation J:143940
decreased trabecular bone mass J:143940
normal skeleton phenotype J:143940
Cthrc1tm1Hssk/Cthrc1tm1Hssk
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1) 		no abnormal phenotype detected J:140886
Cthrc1tm1Vli/Cthrc1tm1Vli
129S6.Cg-Cthrc1tm1Vli 		increased circulating glucose level J:192096
increased liver glycogen level J:192096
increased skeletal muscle glycogen level J:192096
insulin resistance J:192096
Cthrc1tm1Vli/Cthrc1tm1Vli
B6.Cg-Cthrc1tm1Vli 		abnormal hepatocyte morphology J:192096
liver hypoplasia J:192096
macrovesicular hepatic steatosis J:192096
microvesicular hepatic steatosis J:192096
Tg(Col1a1-Cthrc1)1Haak/0
B6.Cg-Tg(Col1a1-Cthrc1)1Haak 		abnormal bone ossification J:143940
abnormal osteoblast physiology J:143940
abnormal trabecular bone morphology J:143940
increased bone mass J:143940
increased bone trabecula number J:143940
increased osteoblast cell number J:143940
increased osteoblast proliferation J:143940
increased trabecular bone mass J:143940
normal skeleton phenotype J:143940
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory