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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
MGI:1915160
26 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Rubcnem1Dgre/Rubcnem1Dgre
C57BL/6-Rubcnem1Dgre
abnormal macrophage physiology J:261225
normal hematopoietic system phenotype J:261225
normal immune system phenotype J:261225
normal mortality/aging J:261225
Rubcnem1Dgre/Rubcnem1Dgre
involves: C57BL/6 * C57BL/6N
abnormal circulating chemokine level J:235399
abnormal kidney morphology J:235399
abnormal macrophage physiology J:235399
abnormal renal glomerulus morphology J:235399
abnormal spleen morphology J:235399
decreased body weight J:235399
decreased circulating interleukin-10 level J:235399
glomerulonephritis J:235399
increased anti-double stranded DNA antibody level J:235399
increased anti-nuclear antigen antibody level J:235399
increased autoantibody level J:235399
increased blood urea nitrogen level J:235399
increased CD8-positive, alpha-beta T cell number J:235399
increased circulating creatinine level J:235399
increased circulating interleukin-1 beta level J:235399
increased circulating interleukin-6 level J:235399
increased circulating interleukin-12b level J:235399
increased IgG level J:235399
increased lymphocyte cell number J:235399
increased monocyte cell number J:235399
increased neutrophil cell number J:235399
increased susceptibility to systemic lupus erythematosus J:235399
increased urine protein level J:235399

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory