Abcg8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abcg8
ATP binding cassette subfamily G member 8
MGI:1914720

45 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Abcg8^{tm1b(KOMP)Wtsi}/Abcg8^{tm1b(KOMP)Wtsi} C57BL/6N-Abcg8^{tm1b(KOMP)Wtsi}/Ccpcz	abnormal cholesterol homeostasis	J:211773
	abnormal heart left ventricle morphology	J:211773
	abnormal lens morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal spleen morphology	J:211773
	cataract	J:211773
	decreased B-2 B cell number	J:211773
	decreased CD4-negative NK T cell number	J:211773
	decreased CD4-positive, alpha-beta T cell number	J:211773
	decreased CD8-positive, alpha-beta T cell number	J:211773
	decreased circulating iron level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased circulating sodium level	J:211773
	decreased hemoglobin content	J:211773
	decreased lung compliance	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	decreased mean corpuscular volume	J:211773
	decreased memory-marker CD4-negative NK T cell number	J:211773
	decreased NK T cell number	J:211773
	decreased T cell number	J:211773
	enlarged liver	J:211773
	enlarged spleen	J:211773
	female infertility	J:211773
	immune system phenotype	J:211773
	impaired righting response	J:211773
	increased cardiac muscle contractility	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating creatinine level	J:211773
	increased circulating potassium level	J:211773
	increased circulating triglyceride level	J:211773
	increased lung elastance	J:211773
	increased mean platelet volume	J:211773
	increased red blood cell distribution width	J:211773
	male infertility	J:211773
Abcg8^tm1Elk/Abcg8⁺ involves: 129S6/SvEvTac * C57BL/6J	abnormal hepatobiliary system physiology	J:94759
Abcg8^tm1Elk/Abcg8⁺ involves: 129S6/SvEvTac * C57BL/6J	decreased circulating cholesterol level	J:94759
Abcg8^tm1Elk/Abcg8^tm1Elk involves: 129S6/SvEvTac * C57BL/6J	abnormal hepatobiliary system physiology	J:94759
	decreased cholesterol level	J:94759
	decreased circulating cholesterol level	J:94759
	decreased fat cell size	J:192806
	decreased white adipose tissue amount	J:192806
	female infertility	J:192806
	increased circulating free fatty acids level	J:192806
	increased circulating phytosterol level	J:94759
	increased circulating triglyceride level	J:94759
	male infertility	J:192806

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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