Pdlim7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pdlim7
PDZ and LIM domain 7
MGI:1914649

32 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pdlim7^em1(IMPC)Mbp/Pdlim7^em1(IMPC)Mbp C57BL/6N-Pdlim7^em1(IMPC)Mbp/MbpMmucd	abnormal liver morphology	J:211773
	abnormal lymph node morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged heart	J:211773
	enlarged lymph nodes	J:211773
	enlarged spleen	J:211773
	increased mean platelet volume	J:211773
	small liver	J:211773
Pdlim7^{Gt(OST445990)Lex}/Pdlim7⁺ B6.129S5-Pdlim7^{Gt(OST445990)Lex}	abnormal cardiac thrombosis	J:209780
	decreased bleeding time	J:209780
	decreased body weight	J:209780
	dilated heart atrium	J:209780
	dilated vasculature	J:209780
	neonatal lethality, incomplete penetrance	J:209780
	postnatal lethality, incomplete penetrance	J:209780
	pulmonary vascular congestion	J:209780
Pdlim7^{Gt(OST445990)Lex}/Pdlim7^{Gt(OST445990)Lex} B6.129S5-Pdlim7^{Gt(OST445990)Lex}	abnormal atrioventricular valve morphology	J:209780
	abnormal cardiac thrombosis	J:209780
	abnormal cardiovascular system physiology	J:209780
	abnormal mitral valve annulus morphology	J:209780
	abnormal mitral valve morphology	J:209780
	abnormal thrombosis	J:209780
	abnormal tricuspid valve annulus morphology	J:209780
	abnormal tricuspid valve morphology	J:209780
	normal cardiovascular system phenotype	J:209780
	decreased bleeding time	J:209780
	decreased body weight	J:209780
	dilated heart atrium	J:209780
	dilated vasculature	J:209780
	normal hematopoietic system phenotype	J:209780
	normal homeostasis/metabolism phenotype	J:209780
	increased lymphocyte cell number	J:209780
	increased monocyte cell number	J:209780
	normal liver/biliary system phenotype	J:209780
	neonatal lethality, incomplete penetrance	J:209780
	postnatal lethality, incomplete penetrance	J:209780
	pulmonary vascular congestion	J:209780

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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