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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Eif2s2
eukaryotic translation initiation factor 2, subunit 2 (beta)
MGI:1914454
13 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Eif2s2em3(IMPC)Bay/Eif2s2+
C57BL/6N-Eif2s2em3(IMPC)Bay/Bay
abnormal coat appearance J:211773
abnormal spleen morphology J:211773
decreased lean body mass J:211773
hemorrhage J:211773
persistence of hyaloid vascular system J:211773
Eif2s2em3(IMPC)Bay/Eif2s2em3(IMPC)Bay
C57BL/6N-Eif2s2em3(IMPC)Bay/Bay
embryonic lethality prior to organogenesis J:211773
preweaning lethality, complete penetrance J:211773
Eif2s2Gt(XH413)Byg/Eif2s2+
129-Eif2s2Gt(XH413)Byg Chr 19MOLF/Ei
decreased incidence of induced tumors J:146879
decreased litter size J:146879
decreased primordial germ cell proliferation J:146879
decreased testis weight J:146879
normal reproductive system phenotype J:146879
Eif2s2Gt(XH413)Byg/Eif2s2Gt(XH413)Byg
involves: 129P2/OlaHsd
embryonic lethality between somite formation and embryo turning, complete penetrance J:146879

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory