Rras2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rras2
related RAS viral (r-ras) oncogene 2
MGI:1914172

31 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rras2^{em1(IMPC)Ccpcz}/Rras2^{em1(IMPC)Ccpcz} C57BL/6NCrl-Rras2^{em1(IMPC)Ccpcz}/Ccpcz	abnormal kidney morphology	J:211773
	abnormal thoracic cage shape	J:211773
	abnormal thymus morphology	J:211773
	abnormal urinary bladder morphology	J:211773
	abnormal uterus morphology	J:211773
	decreased body weight	J:211773
	enlarged thymus	J:211773
	hydrometra	J:211773
	increased NK cell number	J:211773
Rras2^{Gt(OST47398)Lex}/Rras2^{Gt(OST47398)Lex} B6;129S5-Rras2^{Gt(OST47398)Lex}/Ieg	abnormal retina outer plexiform layer morphology	J:82809
	abnormal retina photoreceptor layer morphology	J:82809
	abnormal retina vasculature morphology	J:82809
	increased body size	J:82809
	increased total body fat amount	J:82809
	retina degeneration	J:82809
	thin retina outer nuclear layer	J:82809
Rras2^{Gt(OST361011)Lex}/Rras2⁺ involves: 129S5/SvEvBrd	decreased B cell number	J:151653
	decreased follicular B cell number	J:151653
	decreased marginal zone B cell number	J:151653
	decreased memory T cell number	J:151653
	decreased spleen B cell follicle size	J:151653
	decreased spleen weight	J:151653
	decreased T cell number	J:151653
	maternal effect	J:151653
	spleen hypoplasia	J:151653
Rras2^{Gt(OST361011)Lex}/Rras2^{Gt(OST361011)Lex} B6.129S5-Rras2^{Gt(OST361011)Lex}	decreased B cell number	J:151653
	decreased memory T cell number	J:151653
	decreased T cell number	J:151653
Rras2^{Gt(OST361011)Lex}/Rras2^{Gt(OST361011)Lex} involves: 129S5/SvEvBrd	abnormal B cell activation	J:151653
	abnormal B cell physiology	J:151653
	abnormal CD4-positive, alpha-beta T cell physiology	J:151653
	abnormal CD8-positive, alpha-beta T cell physiology	J:151653
	abnormal lymph node germinal center morphology	J:151653
	decreased B cell number	J:151653
	decreased B cell proliferation	J:151653
	decreased follicular B cell number	J:151653
	decreased marginal zone B cell number	J:151653
	decreased memory T cell number	J:151653
	decreased spleen B cell follicle size	J:151653
	decreased spleen weight	J:151653
	decreased T cell number	J:151653
	maternal effect	J:151653
	spleen hypoplasia	J:151653

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23