Sdhc Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sdhc
succinate dehydrogenase complex, subunit C, integral membrane protein
MGI:1913302

20 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sdhc^{tm1a(EUCOMM)Wtsi}/Sdhc⁺ C57BL/6N-Sdhc^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased bone mineral content	J:175295
	increased bone mineral content	J:175295
Sdhc^{tm1b(EUCOMM)Wtsi}/Sdhc^{tm1b(EUCOMM)Wtsi} C57BL/6N-Sdhc^{tm1b(EUCOMM)Wtsi}/H	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Sdhc^{tm1c(EUCOMM)Wtsi}/Sdhc^{tm1c(EUCOMM)Wtsi} Gt(ROSA)26Sor^{tm1.1(rtTA,tetO-cre)Bkmn}/Gt(ROSA)26Sor⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6N	abnormal blood homeostasis	J:284745
	abnormal muscle physiology	J:284745
	abnormal tricarboxylic acid cycle	J:284745
	decreased circulating glucose level	J:284745
	decreased circulating insulin level	J:284745
	decreased energy expenditure	J:284745
	decreased grip strength	J:284745
	decreased locomotor activity	J:284745
	decreased vertical activity	J:284745
	impaired coordination	J:284745
	increased body fat mass	J:284745
	increased circulating creatine kinase level	J:284745
	lactic acidosis	J:284745
	normal neoplasm	J:284745
	premature death	J:284745
	weight loss	J:284745

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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