Kcne3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kcne3
potassium voltage-gated channel, Isk-related subfamily, gene 3
MGI:1891124

19 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kcne3^{tm1(KOMP)Vlcg}/Kcne3^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal action potential	J:215948
	abnormal hearing electrophysiology	J:215948
Kcne3^{tm1.1(KOMP)Vlcg}/Kcne3^{tm1.1(KOMP)Vlcg} C57BL/6NCrl-Kcne3^{tm1.1(KOMP)Vlcg}/MbpMmucd	abnormal eye morphology	J:211773
	decreased circulating total protein level	J:211773
Kcne3^tm1.1Tjj/Kcne3^tm1.1Tjj involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	abnormal digestive system physiology	J:160721
	abnormal intestine physiology	J:160721
	abnormal physiological response to xenobiotic	J:160721
	abnormal respiratory system physiology	J:160721
Kcne3^tm1Gwab/Kcne3^tm1Gwab B6.Cg-Kcne3^tm1Gwab Tyr^c-2J	normal digestive/alimentary phenotype	J:170745
Kcne3^tm1Gwab/Kcne3^tm1Gwab involves: C57BL/6	abnormal adrenal gland morphology	J:210381
	abnormal cardiovascular system physiology	J:210381
	abnormal T wave	J:210381
	decreased circulating HDL cholesterol level	J:210381
	increased circulating aldosterone level	J:210381
	increased circulating cholesterol level	J:210381
	increased circulating LDL cholesterol level	J:210381
	increased inflammatory response	J:210381
	prolonged QT interval	J:210381
	ventricular tachycardia	J:210381

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23