Dusp12 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dusp12
dual specificity phosphatase 12
MGI:1890614

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ Dusp12^em1Zhzy/Dusp12^em1Zhzy involves: FVB/N	cardiac fibrosis	J:345360
	cardiomyopathy	J:345360
	decreased cardiac muscle contractility	J:345360
	dilated heart ventricle	J:345360
	increased cellular sensitivity to oxidative stress	J:345360
	insulin resistance	J:345360
	myocardium hypertrophy	J:345360
Dusp12^em1(IMPC)Mbp/Dusp12⁺ C57BL/6N-Dusp12^em1(IMPC)Mbp/Ucd	abnormal adrenal gland morphology	J:211773
	increased prepulse inhibition	J:211773
Dusp12^em1(IMPC)Mbp/Dusp12^em1(IMPC)Mbp C57BL/6N-Dusp12^em1(IMPC)Mbp/Ucd	embryonic lethality prior to organogenesis	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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