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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Sit1
suppression inducing transmembrane adaptor 1
MGI:1889342
15 phenotypes from 1 allele in 1 genetic background
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Allelic Composition
Genetic Background
Annotated Term Reference
Sit1tm1Lsmn/Sit1tm1Lsmn
B6.Cg-Sit1tm1Lsmn
abnormal cytokine secretion J:100408
abnormal lymphocyte cell number J:100408
abnormal T cell differentiation J:100408
abnormal T-helper 1 cell differentiation J:100408
decreased CD4-positive, alpha beta T cell number J:100408
decreased CD8-positive, alpha-beta T cell number J:100408
increased double-positive T cell number J:100408
increased interferon-gamma secretion J:100408
increased interleukin-2 secretion J:100408
increased mature gamma-delta T cell number J:100408
increased susceptibility to experimental autoimmune encephalomyelitis J:100408
increased T cell proliferation J:100408
increased tumor necrosis factor secretion J:100408
lymph node hypoplasia J:100408
thymus hyperplasia J:100408

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory