Sit1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sit1
suppression inducing transmembrane adaptor 1
MGI:1889342

15 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Sit1^tm1Lsmn/Sit1^tm1Lsmn B6.Cg-Sit1^tm1Lsmn	abnormal cytokine secretion	J:100408
	abnormal lymphocyte cell number	J:100408
	abnormal T cell differentiation	J:100408
	abnormal T-helper 1 cell differentiation	J:100408
	decreased CD4-positive, alpha-beta T cell number	J:100408
	decreased CD8-positive, alpha-beta T cell number	J:100408
	increased double-positive T cell number	J:100408
	increased interferon-gamma secretion	J:100408
	increased interleukin-2 secretion	J:100408
	increased mature gamma-delta T cell number	J:100408
	increased susceptibility to experimental autoimmune encephalomyelitis	J:100408
	increased T cell proliferation	J:100408
	increased tumor necrosis factor secretion	J:100408
	lymph node hypoplasia	J:100408
	thymus hyperplasia	J:100408

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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