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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dlg3
discs large MAGUK scaffold protein 3
MGI:1888986
17 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Dlg3Gt(P038A02)Wrst/Y
chimera involves: 129S6/SvEvTac * C57BL/6J
abnormal forebrain development J:160967
caudal body truncation J:160967
failure of initiation of embryo turning J:160967
Dlg3tm1a(EUCOMM)Wtsi/Y
C57BL/6N-Dlg3tm1a(EUCOMM)Wtsi/Wtsi
decreased total body fat amount J:211773
increased lean body mass J:211773
Dlg3tm1Grnt/Y
involves: 129P2/OlaHsd * C57BL/6J
abnormal axon morphology J:238576
abnormal barrel cortex morphology J:238576
abnormal brain morphology J:238576
abnormal innervation J:238576
abnormal neocortex size J:238576
abnormal somatosensory cortex morphology J:238576
abnormal synapse morphology J:238576
decreased excitatory postsynaptic current amplitude J:238576
prolonged excitatory postsynaptic current decay time J:238576
Dlg3tm1Grnt/Y
involves: 129P2/OlaHsd * MF1
abnormal locomotor activation J:120078
abnormal long term potentiation J:120078
abnormal spatial learning J:120078

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory