Xpo4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Xpo4
exportin 4
MGI:1888526

22 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Xpo4^em1(IMPC)Tcp/Xpo4⁺ C57BL/6NCrl-Xpo4^em1(IMPC)Tcp/Tcp	abnormal retina morphology	J:211773
	cataract	J:211773
	microphthalmia	J:211773
Xpo4^em1(IMPC)Tcp/Xpo4^em1(IMPC)Tcp C57BL/6NCrl-Xpo4^em1(IMPC)Tcp/Tcp	edema	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Xpo4^em1Gshan/Xpo4⁺ involves: C57BL/6J	abnormal hippocampus neuron morphology	J:330082
	abnormal hippocampus physiology	J:330082
	abnormal spatial reference memory	J:330082
	abnormal spatial working memory	J:330082
	abnormal testis physiology	J:330082
	absent sperm head	J:330082
	asthenozoospermia	J:330082
	coiled sperm flagellum	J:330082
	decreased neuron number	J:330082
	decreased sperm progressive motility	J:330082
	increased cell death	J:330082
	male infertility	J:330082
	oligozoospermia	J:330082
	small testis	J:330082
	teratozoospermia	J:330082
Xpo4^em1Gshan/Xpo4^em1Gshan involves: C57BL/6J	embryonic lethality prior to tooth bud stage	J:330082
Xpo4^{Gt(PT1-ATG)3EVal}/Xpo4^{Gt(PT1-ATG)3EVal} involves: 129S1/Sv * 129X1/SvJ * BALB/c	no abnormal phenotype detected	J:82809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23