Otud5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Otud5
OTU domain containing 5
MGI:1859615

12 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Otud5^{Gt(A021B07)Wrst}/Y chimera involves: 129S2/SvPas	abnormal developmental patterning	J:160967
Otud5^{Gt(A021B07)Wrst}/Y chimera involves: 129S2/SvPas	abnormal embryo turning	J:160967
Otud5^tm1Vmd/Otud5^tm1Vmd Tg(Cd4-cre)1Cwi/0 involves: C57BL/6 * DBA/2	abnormal T-helper 17 cell differentiation	J:219495
	decreased regulatory T cell number	J:219495
	decreased thymocyte number	J:219495
	normal immune system phenotype	J:219495
	increased circulating interleukin-17 level	J:219495
	increased interleukin-9 secretion	J:219495
	increased interleukin-17 secretion	J:219495
	increased interleukin-21 secretion	J:219495
	increased susceptibility to xenobiotic induced morbidity/mortality	J:219495
	intestinal inflammation	J:219495
Otud5^tm1Vmd/Otud5^tm1Vmd Tg(Vav1-cre)#Cgp/0 involves: C57BL/6	abnormal T-helper 17 cell differentiation	J:219495

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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