Reck Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Reck
reversion-inducing-cysteine-rich protein with kazal motifs
MGI:1855698

24 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Reck^tm1.1Noda/Reck^tm2.2Noda involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj	abnormal apical ectodermal ridge morphology	J:184585
	abnormal digit morphology	J:184585
	abnormal forelimb morphology	J:184585
	abnormal limb bud morphology	J:184585
	abnormal limb morphology	J:184585
	absent ulna	J:184585
Reck^tm1Ito/Reck^tm1.1Noda Tg(CAG-cre/Esr1)5Amc/0 involves: 129P2/OlaHsd C57BL/6 * CBA	abnormal blood vessel morphology	J:163845
	abnormal brain vasculature morphology	J:163845
	abnormal developmental vascular remodeling	J:163845
	abnormal liver vasculature morphology	J:163845
	decreased fetal size	J:163845
	dilated vasculature	J:163845
	hemorrhage	J:163845
	lethality throughout fetal growth and development, complete penetrance	J:163845
	pallor	J:163845
Reck^tm1Ito/Reck^tm1Ito either: (involves: 129/Sv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J)	abnormal angiogenesis	J:107674
	abnormal basal lamina morphology	J:107674
	abnormal vascular endothelial cell morphology	J:107674
	abnormal vitelline vascular remodeling	J:107674
	decreased embryo size	J:107674
	embryonic lethality during organogenesis, complete penetrance	J:107674
	internal hemorrhage	J:107674
Reck^tm1Ito/Reck^tm1Ito involves: 129P2/OlaHsd	abnormal blood vessel morphology	J:163845
	abnormal vitelline vascular remodeling	J:163845
	dilated vasculature	J:163845
	hemorrhage	J:163845
Reck^tm2.1Noda/Reck^tm2.2Noda Tg(Col2a1-cre)1Bhr/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	normal limbs/digits/tail phenotype	J:184585
Reck^tm2.1Noda/Reck^tm2.2Noda Tg(Prrx1-cre)1Cjt/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * FVB/N * SJL/J	normal skeleton phenotype	J:184585

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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