Stag3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stag3
STAG3 cohesin complex component
MGI:1355311

5 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Prdm9^em3Kpgn/Prdm9^em3Kpgn Stag3^{tm1e.1(KOMP)Wtsi}/Stag3^{tm1e.1(KOMP)Wtsi} involves: C57BL/6J * C57BL/6N	abnormal double-strand DNA break repair	J:280261
Prdm9^tm1Ymat/Prdm9^tm1Ymat Stag3^{tm1e.1(KOMP)Wtsi}/Stag3^{tm1e.1(KOMP)Wtsi} B6.Cg-Prdm9^tm1Ymat Stag3^{tm1e.1(KOMP)Wtsi}	abnormal double-strand DNA break repair	J:280261
	abnormal male meiosis	J:280261
Rad21l^{tm1b(KOMP)Wtsi}/Rad21l^{tm1b(KOMP)Wtsi} Stag3^{tm1e.1(KOMP)Wtsi}/Stag3^{tm1e.1(KOMP)Wtsi} B6N(Cg)-Rad21l^{tm1b(KOMP)Wtsi} Stag3^{tm1e.1(KOMP)Wtsi}	abnormal double-strand DNA break repair	J:280261
	abnormal synaptonemal complex	J:280261
Rec8^{tm1b(KOMP)Wtsi}/Rec8^{tm1b(KOMP)Wtsi} Stag3^{tm1e.1(KOMP)Wtsi}/Stag3^{tm1e.1(KOMP)Wtsi} B6N(Cg)-Rec8^{tm1b(KOMP)Wtsi} Stag3^{tm1e.1(KOMP)Wtsi}	abnormal double-strand DNA break repair	J:280261
	abnormal male meiosis	J:280261
	abnormal synaptonemal complex	J:280261
Spo11^tm1Mjn/Spo11⁺ Stag3^{tm1e.1(KOMP)Wtsi}/Stag3^{tm1e.1(KOMP)Wtsi} B6.Cg-Spo11^tm1Mjn Stag3^{tm1e.1(KOMP)Wtsi}/2J	abnormal double-strand DNA break repair	J:280261
Stag3^{TgTn(sb-cHS4,Tyr)2312COve}/Stag3^{TgTn(sb-cHS4,Tyr)2312COve} FVB/N-Stag3^{TgTn(sb-cHS4,Tyr)2312COve}	absent oocytes	J:175597
	azoospermia	J:175597

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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