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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Nr4a3
nuclear receptor subfamily 4, group A, member 3
MGI:1352457
22 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Nr4a3tm1Omc/Nr4a3tm1Omc
involves: 129S/SvEv * C57BL/6
abnormal axon extension J:93320
abnormal axon guidance J:93320
abnormal endolymphatic duct morphology J:73971
abnormal hippocampus development J:93320
abnormal hippocampus pyramidal cell layer J:93320
abnormal semicircular canal morphology J:73971
abnormal sulcus ampullaris morphology J:73971
abnormal vestibular system physiology J:73971
bidirectional circling J:73971
decreased hippocampus pyramidal cell number J:93320
hyperactivity J:73971
impaired balance J:73971
increased neuron apoptosis J:93320
increased susceptibility to pharmacologically induced seizures J:93320
loss of hippocampal neurons J:93320
tonic-clonic seizures J:93320
Nr4a3tm1Wnt/Nr4a3+
involves: 129S4/SvJae
abnormal embryonic tissue morphology J:89944
embryonic growth retardation J:89944
prenatal lethality, incomplete penetrance J:89944
Nr4a3tm1Wnt/Nr4a3tm1Wnt
involves: 129S4/SvJae
abnormal embryonic tissue morphology J:89944
abnormal gastrulation J:89944
abnormal gastrulation movements J:89944
embryonic lethality between somite formation and embryo turning, complete penetrance J:89944

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory