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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Abcg5
ATP binding cassette subfamily G member 5
MGI:1351659
43 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Abcg5tm1Plo/Abcg5tm1Plo
involves: 129P2/OlaHsd
abnormal bile secretion J:112995
abnormal cholesterol homeostasis J:112995
abnormal lipid homeostasis J:112995
abnormal liver physiology J:112995
increased liver weight J:112995
Abcg5tm1Plo/Abcg5tm1Plo
involves: 129P2/OlaHsd * C57BL/6J
abnormal liver physiology J:87209
abnormal metabolism J:87209
abnormal phospholipid level J:87209
decreased cholesterol level J:87209
decreased circulating cholesterol level J:87209
enlarged liver J:87209
increased circulating phytosterol level J:87209
increased circulating triglyceride level J:87209
increased circulating VLDL triglyceride level J:87209
Abcg5trac/Abcg5trac
A/J-Abcg5trac
abnormal circulating cholesterol level J:157223
abnormal circulating lipid level J:157223
abnormal erythrocyte osmotic lysis J:157223
abnormal megakaryocyte differentiation J:157223
abnormal megakaryocyte morphology J:157223
abnormal megakaryocyte progenitor cell morphology J:157223
abnormal neutrophil morphology J:157223
abnormal platelet activation J:157223
abnormal platelet alpha-granule morphology J:157223
abnormal platelet morphology J:157223
abnormal spermatogenesis J:157223
anisocytosis J:157223
cardiac fibrosis J:157223
cardiomyopathy J:157223
decreased body size J:157223
decreased hematocrit J:157223
decreased leukocyte cell number J:157223
decreased platelet aggregation J:157223
female infertility J:157223
giant platelets J:157223
hemolytic anemia J:157223
hunched posture J:157223
increased bleeding time J:157223
increased mean platelet volume J:157223
increased megakaryocyte cell number J:157223
male infertility J:157223
premature death J:157223
reticulocytosis J:157223
stomatocytosis J:157223
thrombocytopenia J:157223

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory