About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Abcg5
ATP binding cassette subfamily G member 5
MGI:1351659
73 phenotypes from 3 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Abcg5em1(IMPC)Ccpcz/Abcg5em1(IMPC)Ccpcz
C57BL/6NCrl-Abcg5em1(IMPC)Ccpcz/Ccpcz 		abnormal cholesterol homeostasis J:211773
abnormal cornea morphology J:211773
abnormal heart morphology J:211773
abnormal lens morphology J:211773
abnormal liver morphology J:211773
abnormal spleen morphology J:211773
abnormal tooth color J:211773
abnormal vertebral arch morphology J:211773
decreased CD4-positive, alpha-beta T cell number J:211773
decreased circulating iron level J:211773
decreased circulating serum albumin level J:211773
decreased effector memory T-helper cell number J:211773
decreased lung compliance J:211773
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular volume J:211773
decreased T-helper cell number J:211773
enlarged heart J:211773
enlarged spleen J:211773
increased circulating alanine transaminase level J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating cholesterol level J:211773
increased circulating creatinine level J:211773
increased circulating lactate dehydrogenase level J:211773
increased circulating triglyceride level J:211773
increased fasting circulating glucose level J:211773
increased liver weight J:211773
increased lung elastance J:211773
increased lung tissue damping J:211773
increased red blood cell distribution width J:211773
increased spleen weight J:211773
male infertility J:211773
Abcg5tm1Plo/Abcg5tm1Plo
involves: 129P2/OlaHsd 		abnormal bile secretion J:112995
abnormal cholesterol homeostasis J:112995
abnormal lipid homeostasis J:112995
abnormal liver physiology J:112995
increased liver weight J:112995
Abcg5tm1Plo/Abcg5tm1Plo
involves: 129P2/OlaHsd * C57BL/6J 		abnormal liver physiology J:87209
abnormal metabolism J:87209
abnormal phospholipid level J:87209
decreased cholesterol level J:87209
decreased circulating cholesterol level J:87209
decreased fat cell size J:192806
decreased white adipose tissue amount J:192806
enlarged liver J:87209
female infertility J:192806
increased circulating phytosterol level J:87209
increased circulating triglyceride level J:87209
increased circulating VLDL triglyceride level J:87209
male infertility J:192806
Abcg5trac/Abcg5trac
A/J-Abcg5trac 		abnormal circulating cholesterol level J:157223
abnormal circulating lipid level J:157223
abnormal megakaryocyte differentiation J:157223
abnormal megakaryocyte morphology J:157223
abnormal megakaryocyte progenitor cell morphology J:157223
abnormal neutrophil morphology J:157223
abnormal platelet activation J:157223
abnormal platelet alpha-granule morphology J:157223
abnormal platelet morphology J:157223
abnormal spermatogenesis J:157223
anisocytosis J:157223
cardiac fibrosis J:157223
cardiomyopathy J:157223
decreased body size J:157223
decreased hematocrit J:157223
decreased leukocyte cell number J:157223
decreased platelet aggregation J:157223
female infertility J:157223
giant platelets J:157223
hemolytic anemia J:157223
hunched posture J:157223
increased bleeding time J:157223
increased erythrocyte osmotic fragility J:157223
increased mean platelet volume J:157223
increased megakaryocyte cell number J:157223
male infertility J:157223
premature death J:157223
reticulocytosis J:157223
stomatocytosis J:157223
thrombocytopenia J:157223
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory