Abcd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abcd1
ATP-binding cassette, sub-family D member 1
MGI:1349215

23 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Abcd1^{tm1a(EUCOMM)Wtsi}/Y B6JTyr;B6N-Abcd1^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal lens morphology	J:165965
	cataract	J:165965
	no abnormal phenotype detected	J:213427
Abcd1^tm1Kan/Y involves: 129 * BALB/cJ * C57BL/6J * Swiss	increased fatty acids level	J:257393
Abcd1^tm1Kan/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal lipid homeostasis	J:44812
Abcd1^tm1Kan/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	reduced fertility	J:44812
Abcd1^tm1Kan/Abcd1^tm1Kan involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal lipid homeostasis	J:44812
	reduced fertility	J:44812
Abcd1^tm1Kds/Y either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129/Sv * 129S4/SvJae * C57BL/6)	abnormal lipid homeostasis	J:42479
	increased saturated fatty acids level	J:42479
Abcd1^tm1Kds/Y involves: 129S4/SvJae * C57BL/6J	abnormal adrenal cortex morphology	J:94583
	abnormal adrenal gland zona fasciculata morphology	J:94583
	abnormal adrenal gland zona reticularis morphology	J:94583
	abnormal astrocyte morphology	J:94583
	abnormal locomotor activation	J:94583
	abnormal microglial cell morphology	J:94583
	abnormal myelination	J:94583
	abnormal nerve conduction	J:94583
	abnormal nervous system physiology	J:94583
	abnormal spinal cord morphology	J:94583
	astrocytosis	J:94583
	axon degeneration	J:94583
	impaired coordination	J:94583
	increased fatty acids level	J:94583
Abcd1^tm1Kds/Abcd1^tm1Kds either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129/Sv * 129S4/SvJae * C57BL/6)	abnormal lipid homeostasis	J:42479
	increased saturated fatty acids level	J:42479
Abcd1^tm1Kds/Abcd1^tm1Kds involves: 129/Sv * 129S4/SvJae * C57BL/6J	abnormal motor coordination/balance	J:75388
	abnormal myelination	J:75388
	abnormal nerve conduction	J:75388
	abnormal Schwann cell morphology	J:75388
	axon degeneration	J:75388
	decreased vertical activity	J:75388
	impaired coordination	J:75388
Abcd1^tm1Ymd/Y involves: 129S/SvEv * C57BL/6J * DBA/2J	abnormal lipid homeostasis	J:40230
Abcd1^tm1Ymd/Abcd1^tm1Ymd involves: 129S/SvEv * C57BL/6J * DBA/2J	abnormal lipid homeostasis	J:40230

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23