Psmb9 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
MGI:1346526

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Psmb9^tm1Stl/Psmb9^tm1Stl Trp53^tm1Brd/Trp53^tm1Brd involves: 129P2/OlaHsd * C57BL/6	increased lymphoma incidence	J:67509
	increased sarcoma incidence	J:67509
	increased tumor incidence	J:67509
Psmb10^tm1Mgro/Psmb10^tm1Mgro Psmb9/Psmb8^tm1Klr/Psmb9/Psmb8^tm1Klr B6.129-Psmb10^tm1Mgro Psmb9/Psmb8^tm1Klr	abnormal antigen presentation via MHC class I	J:180765
	abnormal B lymphocyte antigen presentation	J:180765
	abnormal dendritic cell antigen presentation	J:180765
	decreased CD8-positive, alpha-beta T cell number	J:180765
	decreased level of surface class I molecules	J:180765

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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