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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bub3
BUB3 mitotic checkpoint protein
MGI:1343463
16 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bub3tm1Jvd/Bub3+
Rae1tm1Jvd/Rae1+
Not Specified 		abnormal cell cycle checkpoint function J:105717
abnormal cellular replicative senescence J:105717
abnormal mitosis J:81546, J:105717
aneuploidy J:81546, J:105717
cachexia J:105717
cataract J:105717
decreased cell proliferation J:81546
decreased subcutaneous adipose tissue amount J:105717
decreased total body fat amount J:105717
increased incidence of tumors by chemical induction J:81546
lordokyphosis J:105717
muscle degeneration J:105717
muscular atrophy J:105717
premature aging J:105717
thin dermal layer J:105717
weight loss J:105717
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory