Kcnh3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
MGI:1341723

17 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kcnh3^{tm1.1(KOMP)Vlcg}/Kcnh3⁺ C57BL/6N-Kcnh3^{tm1.1(KOMP)Vlcg}/J	abnormal retina morphology	J:211773
	increased circulating free fatty acids level	J:211773
Kcnh3^{tm1.1(KOMP)Vlcg}/Kcnh3^{tm1.1(KOMP)Vlcg} C57BL/6N-Kcnh3^{tm1.1(KOMP)Vlcg}/J	abnormal retina morphology	J:211773
	hyperactivity	J:211773
	improved glucose tolerance	J:211773
	increased fasting circulating glucose level	J:211773
	increased hemoglobin content	J:211773
Kcnh3^tm1.1Tije/Kcnh3^tm1.1Tije involves: C57BL/6	abnormal single cell response	J:165296
Kcnh3^tm1.1Tije/Kcnh3^tm1.1Tije involves: C57BL/6	decreased single cell response threshold	J:165296
Kcnh3^tm1.2Tije/Kcnh3⁺ involves: C57BL/6	abnormal spike wave discharge	J:165296
Kcnh3^tm1.2Tije/Kcnh3^tm1.2Tije involves: C57BL/6	abnormal single cell response	J:165296
	abnormal spike wave discharge	J:165296
	normal behavior/neurological phenotype	J:165296
	decreased single cell response threshold	J:165296
	increased susceptibility to pharmacologically induced seizures	J:165296
	nonconvulsive seizures	J:165296
Kcnh3^tm1Akmi/Kcnh3⁺ involves: 129S4/SvJae * C57BL/6	abnormal long-term object recognition memory	J:155749
Kcnh3^tm1Akmi/Kcnh3⁺ involves: 129S4/SvJae * C57BL/6	abnormal spatial reference memory	J:155749
Kcnh3^tm1Akmi/Kcnh3^tm1Akmi involves: 129S4/SvJae * C57BL/6	abnormal CNS synaptic transmission	J:155749
	abnormal long-term object recognition memory	J:155749
	abnormal long-term potentiation	J:155749
	abnormal spatial reference memory	J:155749
	abnormal spatial working memory	J:155749

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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