Agpat3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
MGI:1336186

25 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Agpat3^{tm1a(EUCOMM)Wtsi}/Agpat3⁺ B6JTyr;B6N-Agpat3^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased bone mineral content	J:175295
	decreased circulating alanine transaminase level	J:175295
	decreased circulating aspartate transaminase level	J:175295
	decreased lactate dehydrogenase level	J:175295
Agpat3^{tm1a(EUCOMM)Wtsi}/Agpat3^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Agpat3^{tm1a(EUCOMM)Wtsi}/Wtsi	preweaning lethality, incomplete penetrance	J:211773
Agpat3^{tm1a(EUCOMM)Wtsi}/Agpat3^{tm1a(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N	abnormal phospholipid level	J:246569
	abnormal photoreceptor inner segment morphology	J:246569
	abnormal photoreceptor outer segment disc membrane morphology	J:246569
	abnormal photoreceptor outer segment morphology	J:246569
	abnormal retina morphology	J:246569
	abnormal vision	J:246569
	decreased a-wave amplitude	J:246569
	decreased b-wave amplitude	J:246569
	disorganized photoreceptor inner segment	J:246569
	disorganized photoreceptor outer segment	J:246569
	retina degeneration	J:246569
	short photoreceptor inner segment	J:246569
	short photoreceptor outer segment	J:246569
	thin retina outer nuclear layer	J:246569
Agpat3^{tm1a(EUCOMM)Wtsi}/Agpat3^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	abnormal phospholipid level	J:245638
	abnormal Sertoli cell morphology	J:245638
	abnormal sperm head morphology	J:245638
	impaired fertilization	J:245638
	male infertility	J:245638
	oligozoospermia	J:245638
	teratozoospermia	J:245638

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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