Top3b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Top3b
topoisomerase (DNA) III beta
MGI:1333803

18 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Top3b^tm1Jcw/Top3b⁺ involves: 129S6/SvEvTac * C57BL/6	premature death	J:69405
Top3b^tm1Jcw/Top3b^tm1Jcw involves: 129S6/SvEvTac * C57BL/6	abnormal kidney morphology	J:69405
	abnormal lung morphology	J:69405
	abnormal male meiosis	J:82397
	abnormal salivary gland morphology	J:69405
	aneuploidy	J:82397
	decreased litter size	J:82397
	dermatitis	J:69405
	early reproductive senescence	J:82397
	enlarged axillary lymph nodes	J:69405
	enlarged spleen	J:69405
	enlarged submandibular lymph nodes	J:69405
	glomerulonephritis	J:69405
	increased inflammatory response	J:69405
	pancreas inflammation	J:69405
	pancreatic islet hyperplasia	J:69405
	premature death	J:69405
	reduced female fertility	J:82397
	stomach inflammation	J:69405

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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