Il18bp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il18bp
interleukin 18 binding protein
MGI:1333800

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il18bp^{tm1(KOMP)Vlcg}/Il18bp^{tm1(KOMP)Vlcg} C57BL/6-Il18bp^{tm1(KOMP)Vlcg}	abnormal NK cell differentiation	J:255309
	decreased interferon-gamma secretion	J:255309
	decreased KLRG1-positive NK cell number	J:255309
	decreased mature NK cell number	J:255309
	decreased NK cell number	J:255309
	normal growth/size/body region phenotype	J:255309
	increased circulating interferon-gamma level	J:255309
	increased immature NK cell number	J:255309
Il18bp^{tm1.1(KOMP)Vlcg}/Il18bp^{tm1.1(KOMP)Vlcg} involves: C57BL/6N	abnormal circulating chemokine level	J:261967
	abnormal lymph node morphology	J:261967
	abnormal macrophage activation involved in immune response	J:261967
	abnormal phagocyte morphology	J:261967
	abnormal spleen morphology	J:261967
	enlarged liver	J:261967
	enlarged spleen	J:261967
	normal immune system phenotype	J:261967
	increased B cell number	J:261967
	increased circulating alanine transaminase level	J:261967
	increased circulating ferritin level	J:261967
	increased circulating interferon-gamma level	J:261967
	increased circulating interleukin-18 level	J:261967
	increased macrophage cell number	J:261967
	increased monocyte cell number	J:261967
	pancytopenia	J:261967
	weight loss	J:261967

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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