Mpp3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mpp3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MGI:1328354

15 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mpp3^tm1.1Wij/Mpp3^tm1.1Wij Emx1^tm1(cre)Ito/Emx1⁺ involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J	abnormal cerebral cortex morphology	J:198427
	abnormal mitotic spindle morphology	J:198427
	abnormal neuronal migration	J:198427
	increased mitotic index	J:198427
Mpp3^tm1.1Wij/Mpp3^tm1.1Wij Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JOlaHsd * FVB/N * SJL	abnormal electroretinogram waveform feature	J:199562
	abnormal retina morphology	J:199562
	abnormal retina outer limiting membrane morphology	J:199562
	abnormal retina outer nuclear layer morphology	J:199562
Mpp3^tm1.1Wij/Mpp3^tm1.1Wij Tg(rx3-icre)1Mjam/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JOlaHsd * FVB/N	abnormal electroretinogram waveform feature	J:199562
	abnormal retina morphology	J:199562
	abnormal retina outer limiting membrane morphology	J:199562
	abnormal retina outer plexiform layer morphology	J:199562
	increased susceptibility to age-related retinal degeneration	J:199562
	retina degeneration	J:199562
Mpp3^{tm1b(EUCOMM)Wtsi}/Mpp3^{tm1b(EUCOMM)Wtsi} C57BL/6N-Mpp3^{tm1b(EUCOMM)Wtsi}/BayMmucd	abnormal heart left ventricle morphology	J:211773
	decreased circulating glucose level	J:211773
	increased cardiac muscle contractility	J:211773
	thick ventricular wall	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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