Ptprt Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptprt
protein tyrosine phosphatase receptor type T
MGI:1321152

14 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ptprt^m1Rgsc/Ptprt^m1Rgsc C57BL/6J-Ptprt^m1Rgsc	abnormal excitatory synapse morphology	J:298303
	abnormal inhibitory synapse morphology	J:298303
	abnormal miniature inhibitory postsynaptic currents	J:298303
	behavioral despair	J:298303
	decreased gamma-aminobutyric acid level	J:298303
	decreased glutamine level	J:298303
	enhanced long-term potentiation	J:298303
	impaired neuron differentiation	J:298303
Ptprt^tm1Sata/Ptprt^tm1Sata B6.129P2-Ptprt^tm1Sata	increased colon adenoma incidence	J:157542
Ptprt^tm1Sata/Ptprt^tm1Sata B6.129P2-Ptprt^tm1Sata	increased incidence of tumors by chemical induction	J:157542
Ptprt^tm1Sata/Ptprt^tm1Sata involves: 129P2/OlaHsd	normal behavior/neurological phenotype	J:298303
	behavioral despair	J:298303
	decreased gamma-aminobutyric acid level	J:298303
	decreased miniature inhibitory postsynaptic current frequency	J:298303
	decreased neuronal stem cell self-renewal	J:298303
	enhanced long-term potentiation	J:298303
	normal homeostasis/metabolism phenotype	J:298303
	impaired neuron differentiation	J:298303

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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