Casq2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Casq2
calsequestrin 2
MGI:1309469

22 phenotypes from 7 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Casq2^tm1.1Sgp/Casq2^tm1.1Sgp involves: 129X1/SvJ * C57BL/6NCrL	abnormal myocardial fiber morphology	J:151367
	abnormal myocardial fiber physiology	J:151367
	ventricular premature beat	J:151367
	ventricular tachycardia	J:151367
Casq2^{tm1b(KOMP)Wtsi}/Casq2⁺ C57BL/6N-Casq2^{tm1b(KOMP)Wtsi}/Ucd	abnormal sinus arrhythmia	J:211773
	cardiovascular system phenotype	J:211773
	decreased heart rate variability	J:211773
Casq2^{tm1b(KOMP)Wtsi}/Casq2^{tm1b(KOMP)Wtsi} C57BL/6N-Casq2^{tm1b(KOMP)Wtsi}/Ucd	edema	J:211773
	preweaning lethality, complete penetrance	J:211773
Casq2^tm1Jse/Casq2^tm1Jse involves: FVB/N	abnormal myocardial fiber physiology	J:124211
	abnormal sinus arrhythmia	J:124211
	cardiac hypertrophy	J:124211
	decreased heart rate	J:124211
	decreased ventricle muscle contractility	J:124211
	heart left ventricle hypertrophy	J:124211
	increased heart atrium size	J:124211
	increased response of heart to induced stress	J:124211
	ventricular premature beat	J:124211
	ventricular tachycardia	J:124211
Casq2^tm1Kpfe/Casq2^tm1Kpfe involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal myocardial fiber physiology	J:114621
	decreased heart rate	J:114621
	increased heart weight	J:114621
	thick ventricular wall	J:114621
	ventricular tachycardia	J:114621
Casq2^tm2.1Sgp/Casq2^tm2.1Sgp involves: 129	abnormal myocardial fiber morphology	J:212671
	abnormal sarcoplasmic reticulum morphology	J:212671
	ventricular tachycardia	J:212671
Casq2^tm2Jse/Casq2^tm2Jse Not Specified	abnormal myocardial fiber physiology	J:124211
	abnormal sinus arrhythmia	J:124211
	cardiac hypertrophy	J:124211
	decreased heart rate	J:124211
	decreased ventricle muscle contractility	J:124211
	heart left ventricle hypertrophy	J:124211
	increased heart atrium size	J:124211
	increased response of heart to induced stress	J:124211
	ventricular premature beat	J:124211
	ventricular tachycardia	J:124211
Tg(Myhca-Casq2)418Egk/0 involves: FVB/N	abnormal cardiac muscle relaxation	J:50498
	abnormal cardiovascular system physiology	J:50498
	abnormal myocardial fiber physiology	J:50498
	cardiac hypertrophy	J:50498
	decreased cardiac muscle contractility	J:50498
	increased myocardial fiber size	J:50498

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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